Diagnostic Utility Of Fluid Cytology By Conventional Smear And Cell Block Method In Pleural Effusion
The cytological examinations of serous effusions have been well-accepted, and a positive diagnosis is often considered a definitive
diagnosis. The study was planned to determine the diagnostic utility of fluid cytology by conventional smear and cell block method in pleural
effusion. This was a hospital-based open cohort observational study conducted on patients diagnosed with pleural effusion. The study
period was one year, and patients were recruited using a nonprobability sampling method. The fluid samples were subjected to the
conventional smear examination, followed by cell block preparation. The overall morphologic details, cellularity, architecture, and nuclear
and cytoplasmic details were studied and compared in conventional smear and cell block techniques. The samples were categorized as
unsatisfactory, benign, suspicious for malignancy, or malignancy. The study was conducted on 113 pleural fluid samples. The study
demonstrated that the cell block technique improved the cellular yield and established diagnosis in malignant effusions.
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