In recent times, especially during the antibiotic resistance era, it is crucial to find active and sustainable alternatives that work against microbes. In this study, seven plants Minuartia nifensis McNeill, Sideritis sipylea Boiss, Asperula daphneola O.Schwarz, Teucrium montanum L, Stachys cretica L. subsp, Smyrnaea rech. Fil and Euphorbia erythrodon Boiss/Heldr growing in Turkey were collected and newly registered. Alcoholic extracts were prepared to investigate their antimicrobial and antioxidant activity. These plants are widespread in the mountains of Izmir City (Turkey). Three assessments were performed in this project: agar well diffusion method, a standard antimicrobial (antibacterial and anti-fungal) activity test, followed by MIC test, which determines the lowest concentration and lowest quantity that affects microbes after adding resazurin indicator, and finally, antioxidant activity by ELISA microplate reader. The findings showed activity against S. aureus and E. colį. Antifungal activity against C. albįcans and C. glabrata was the highest activity shown by most extracts. Antioxidant activity was also confirmed by quantification of radical scavenging activity via DPPH assay.