This research seeks to analyze the effects of the Mexican trade balance on the basis of the Mexico-Japan Economic Partnership Agreement period 2005-2017. The research question is, What are the effects of the Mexican trade balance during the period 2005-2017 in terms of Mexico-Japan Economic Association Agreement (AAEMJ)? The research method used is empirical-analytical and documentary. It is observed that the AAEMJ has strengthened the economic relationship between both countries; however, it has a trade deficit with Japan of 12 million dollars, and the growth of imports is due to establishment of Japan’s foreign direct investment (FDI) in Mexico. Mexican exports need support and development programs.